Carbon Capture, Utilization, and Storage (CCUS) technology is one of the key approaches to address global climate change and achieve carbon dioxide emission reduction. As a core component of the CCUS technology system, CO₂ geological storage will play a foundational supporting role in the process of achieving the carbon neutrality goal in China's energy industry. Currently, the main geological formations for CO₂ storage include deep saline aquifers, depleted oil and gas reservoirs, deep unmineable coal seams, and basalts. Due to differences in rock properties and geological conditions, different geological formations have formed distinct storage mechanisms and models. Based on a systematic analysis of CO₂ storage mechanisms in different geological formations, combined with typical domestic and international engineering cases, this paper summarizes the implementation effects and applicable conditions of various storage technologies. Additionally, aiming at the current technical bottlenecks and safety risks of CO₂ geological storage, this article discusses the future technical development directions and industrialization paths, in order to provide theoretical support and practical reference for promoting the large-scale application of CO₂ geological storage technology in China.

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Increasing evidence indicates that the vaginal microbiota (VMB) is closely associated with the development and progression of cervical diseases. Alterations in microbial composition have been observed across different stages of human papillomavirus (HPV) infection, cervical intraepithelial neoplasia (CIN), and cervical cancer. In healthy individuals, the VMB is typically dominated by Lactobacillus species, which contribute to the maintenance of an acidic environment and local immune balance. In contrast, vaginal dysbiosis is characterized by a reduction in Lactobacillus and an increased abundance of anaerobic bacteria, accompanied by elevated pH, disruption of epithelial barriers, and persistent inflammatory responses. Clinical and sequencing studies have reported that enrichment of specific bacterial genera, including Sneathia and Fusobacterium, is more frequently detected in high-grade cervical lesions, suggesting a potential association with disease severity. These microbial shifts may facilitate persistent HPV infection and promote lesion progression through multiple biological pathways. In addition, emerging evidence suggests that modulation of the VMB, particularly through probiotic supplementation with Lactobacillus crispatus, may support HPV clearance and improve microbial stability in early disease stages. By integrating findings from recent studies, this review outlines the dynamic changes of key microbial taxa during cervical disease progression and discusses their potential clinical relevance. These observations provide a quantitative reference for future investigations and highlight the possible value of microbiome-based strategies in cervical disease risk assessment and management.

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Ischemic stroke can be treated through anti-inflammation pathway.Coicis Semen is a kind of common traditional herbal medicine with long history. It is a Chinese medicine for both treatment and food. It contains fatty acids and esters, polysaccharides, flavonoids, triterpenes, alkaloids, sterols, lactam, starch, and other compounds, which play different effects and achieve the purpose of treatment. It has been proven to protect against ischemic stroke in TGFβ/ALK1 signaling pathway, which stimulates angiogenesis. This project aims to verify if Coicis Semen can treat ischemic stroke in anti-inflammation pathway. Both inflammatory factors and neutrophils were tested. Inflammatory factors were collected from bEnd.3 cells. The expression level of P-NF-kB, P-IkB and HIF-1α was evaluated by Western Blot. The production of NO was analyzed through Griess reaction. Zebrafish was applied to mimic the neutrophil production in ischemic stroke. The neutrophils in zebrafish embryos were stained by Sudan black and could be observed under optical microscope. Coicis Semen had positive effect on inhibiting expression of inflammatory factors and production of neutrophils. It can be proven that Coicis Semen treating ischemic stroke in anti-inflammation pathway is feasible.

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Due to observational studies on the role of type of food in have been inconsistent, the objective of this study was to apply the MR framework to evaluate the causal link between dietary intake and gastric ulcer to provide suggestions for preventive intervention strategies. Mendelian randomization test was conducted to assess the impact of 26 types of dietary habits and macronutrient intake on of GC and precancerous lesions. Genetically predicted alcoholic drinks per week were strongly connected with. Potential evidence , fat, and cooked vegetable intake might increase tumors. Salad/raw vegetable intake may decrease . Dietary composition and habits are causally related to GC and precancerous lesions. The biological heterogeneity of food processed in different ways and type of food may be a risk factor for GC. Intensive attention should be paid to lifestyle and diet management.

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